Photo of Tracy Y. Wang, MD, MHS, MSc, Chief of Comparative Clinical Effectiveness Research at the Patient-Centered Outcomes Research Institute (PCORI).

Tracy Y. Wang, MD, MHS, MSc, is Chief of Comparative Clinical Effectiveness Research at the Patient-Centered Outcomes Research Institute (PCORI). She is a cardiologist and clinical researcher with expertise in observational research, implementation science, and pragmatic randomized clinical trials.

Wang leads PCORI’s comparative effectiveness research portfolio focused on increasing the evidence base for existing interventions and emerging innovations to improve health outcomes and health equity through multidisciplinary research. She provides strategic guidance and oversight of ongoing programs and new initiatives designed to enhance and accelerate patient-centered comparative effectiveness research.

Prior to her current role, Wang was Professor of Medicine at Duke University and led several large studies at the Duke Clinical Research Institute that have focused on comparative effectiveness and safety, health disparities, care quality assessment, and quality improvement. To date, she has published over 350 peer-reviewed manuscripts, lectured widely on pragmatic trials and the use of data to guide initiatives aimed at reducing disparities in healthcare access and outcomes. Additionally, she has evolved the platform for research to diversify site and patient recruitment, innovate longitudinal patient follow-up, enrich the collection of patient-reported outcomes, and pragmatically adjudicate clinical events of interest. She previously served as Assistant Dean of Continuing Medical Education and Director of Health Services and Outcomes Research at Duke.

Wang has served on numerous volunteer committees, tasks forces, and writing groups for the American Heart Association, American College of Cardiology, and American College of Physicians. She previously chaired the AHA Council Operations Committee (2020-22) and AHA’s Quality of Care and Outcomes Research (QCOR) Council (2017-19). She is an Associate Editor of the JAMA Internal Medicine journal and serves on the editorial boards of several other high-impact journals. In 2022, she was awarded the American Heart Association QCOR Outstanding Lifetime Achievement Award, and has received multiple awards recognizing her excellence in mentorship and leadership in enhancing diversity in both research participants and workforce.

An undergraduate of Yale University, Wang received her MD from Harvard Medical School, MSc in molecular biochemistry and biophysics from Yale University, and MHS in clinical research from Duke University. 



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