Resources
Search a collection of resources that have been developed for prospective PCORI funding applicants and funding awardees, as well as patients, caregivers and members of the broader healthcare community. Find information on an array of topics, including comparative clinical effectiveness research (CER), engagement in research, dissemination and implementation and more. In addition, view PCORI's Evidence Updates that capture the highlights and context for new findings in an easy-to-digest format.
Patient-Centered Outcomes Data Repository (PCODR)
PCODR offers a collection of patient-centered CER data from a growing number of PCORI-funded studies.
Learn More & Access the RepositoryDisplaying 1 - 25 of 69 results
Awardee Resource
Cost Considerations: Description of Allowable Direct Costs under a PCORI Award
Used by PCORI to evaluate the allowability and reasonableness of budgets submitted through the application process and costs incurred in the performance of the Research Project.
Topic Brief
Topic Brief: Infantile Epilepsy
Epilepsy is more common in children than adults, with several epilepsy syndromes exclusive to the pediatric population. In this Topic Brief, the authors identified 401 relevant empirical studies reporting specifically…
Awardee Resource
Sample Invoice Template
Invoices submitted to PCORI must contain all of the information requested in the Sample Invoice Template to allow PCORI to examine costs incurred during the Research Project.
Awardee Resource
Draft Final Research Report Appendix: PCORI Methodology Standards Checklist
This report documents Research Project findings and other information, including for purposes of peer review by PCORI, consistent with the PCORI Peer Review and Findings Release Process.
Legal and Financial Document
PCORI Bylaws
PCORI's Bylaws are PCORI’s Board-approved governance framework for PCORI’s operations and management, consistent with PCORI’s authorizing law and the District of Columbia Nonprofit Corporation Act.
Applicant Resource
Cost Principles: Description of Allowable Direct Costs Under a PCORI Award (2022)
The PCORI Cost Principles, in conjunction with the applicable award/contract terms and conditions, serve as a means for identifying expenses that are considered allowable under a PCORI award/contract. (Effective Cycle…
Applicant Resource
PCORI's Foundational Expectations for Partnerships in Research
PCORI has developed six foundational expectations—building blocks for meaningful, effective, and sustainable engagement with patients, communities, and other partners in research. Building on recent evidence and PCORI awardees’ experiences with…
Research Resource
PCORI Horizon Scanning Database
The PCORI Health Care Horizon Scanning Database offers healthcare decision makers findings about advancements in six key areas of interest. Alzheimer's Disease and Other Dementias Cancer Cardiovascular and Cardiometabolic Conditions…
Evidence Update
Managing Mild Asthma in Children Age Six and Older (Evidence Update for Parents)
Asthma is a common chronic illness among children in the US, with disproportionate impact among racial and ethnic minorities. A PCORI-funded study looked at two different approaches to managing mild…
Evidence Update
Treating Depression When You're on Dialysis (Evidence Update for Patients)
Depression is common in people who are on dialysis and can affect kidney health, as well as overall well-being. A PCORI-funded study looked at how well two treatments for depression…
Evidence Update
Comparing General Versus Spinal Anesthesia for Hip Fracture Surgery (Evidence Update for Clinicians)
Each year, more than 300,000 older adults in the United States fracture a hip. The impact on health outcomes and quality of life can be severe. Most people need surgery…
Evidence Update
Comparing Two Kinds of Anesthesia Used During Hip Fracture Surgery (Evidence Update for Patients)
Each year, more than 300,000 older adults in the United States fracture a hip. The impact on health outcomes and quality of life can be severe. Most people need surgery…
Research Resource
Landscape Review and Summary of Patient and Stakeholder Perspectives on Value in Health and Health Care
This landscape review of perspectives on "value" in health and health care in the United States, with a focus on PCORI’s stakeholders—patients and caregivers, clinicians, payers, purchasers, hospitals/health systems, industry…
Evidence Update
Comparing Two Treatments for Resistant Kawasaki Disease (Evidence Update for Parents)
Kawasaki disease (KD) is a rare disease that most commonly affects children. KD can be treated, but some children have resistant KD and do not respond to initial treatment. The…
Evidence Update
Comparing Two Treatments for IVIG-Resistant Kawasaki Disease (Evidence Update for Clinicians)
Kawasaki disease (KD) is a rare disease that most commonly affects children. KD can be treated, but some children have resistant KD and do not respond to initial treatment. The…
Research Resource
Principles for the Consideration of the Full Range of Outcomes Data in PCORI-Funded Research
In March 2021, PCORI's Board of Governors approved a set of four Principles for the Consideration of the Full Range of Outcomes Data in PCORI-Funded Research, which will guide how…
Evidence Update
Comparing Treatments for Multiple Sclerosis-Related Fatigue (Evidence Update for Clinicians)
It can be hard to enjoy life if you’re always tired. But many people with multiple sclerosis (MS) experience fatigue, which can affect quality of life and make it hard…
Evidence Update
Treatment Options for Genitourinary Syndrome of Menopause (Evidence Update for Clinicians
Genitourinary syndrome of menopause (GSM) describes the symptoms caused by hormonal changes during and after menopause. It includes a spectrum of symptoms that affect quality of life for more than…
Evidence Update
Identifying and Treating Obsessive-Compulsive Disorder in Children and Teens (Evidence Update for Clinicians)
Obsessive-compulsive disorder, or OCD, is a mental health condition in which children have intense obsessions or compulsions that get in the way of everyday life. A recent review of research…
Awardee Resource
PCORI Policy for Data Management and Data Sharing
This policy calls for the researchers PCORI funds to share their data sets and documentation for reanalysis and reuse. The policy advances PCORI’s commitment to open science by encouraging use…
Legal and Financial Document
In Brief: PCORI Funding Reauthorization
In 2019, Congress passed legislation that reauthorized funding for PCORI and amended our original authorizing statute. Key provisions of the 2019 law are outlined in this brief.
Research Resource
Changes to Telehealth Policy, Delivery, and Outcomes in Response to COVID-19: A Landscape Review
This report provides a rich summary of changes under the COVID-19 pandemic and highlights some areas in telehealth where additional research may be valuable. Background (December 2020) — During the…
Applicant Resource
Budgeting for Engagement Activities
PCORI is committed to ensuring that patients and caregivers are meaningfully engaged in all aspects of research. To achieve this, PCORI requires that its funded projects demonstrate a commitment to…
Legal and Financial Document
Board & Methodology Committee Compensation and Reimbursement (Policy)
The Board & Methodology Committee Compensation and Reimbursement Purpose policy establishes rules for the compensation and reimbursement of members of the Board and Methodology Committee in accordance with the Institute’s…
Applicant Resource
Strategies to Leverage PCORnet® to Advance PCORI's National Priorities for Health and Evaluate PCORnet Performance
PCORI first invested in the development of PCORnet ®, the National Patient-Centered Clinical Research Network, in 2013. PCORnet® addresses PCORI’s National Priority to build infrastructure to accelerate patient-centered outcomes research…