Final Research Report

View this project's final research report.

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Peer-Review Summary

Peer review of PCORI-funded research helps ensure that research reports present complete, balanced, useful information about the research. It also examines how well the research has followed the PCORI Methodology Standards. During peer review, experts who were not members of the research team read a draft report of the research. These experts may include a scientist focused on the research topic, a specialist in research methods, a patient or caregiver, and a healthcare professional. Reviewers do not benefit from the results of the research (e.g., no conflicts of interest).

Peer reviewers point out where the draft report may need revision. For example, they may suggest ways to improve how the research team analyzed results, reported conclusions, or listed shortcomings. Learn more about PCORI’s peer review process here.

In response to peer review, the PI made revisions including:

  • Adding further explanation of why the study sample might not be typical of all groups of adolescents and young adults with similar health problems
  • Describing more fully the work the study team did to develop better ways for study participants to express how study interventions affected them
  • Providing more information about how researchers extracted information from interviews with adolescent/young adults and parents to determine their preferences about cholesterol screening and treatment
  • Explaining in more detail the pros and cons of screening children for hypercholesterolemia (versus just adults) to inform patients, caregivers, and clinicians about which screening strategy is best

Conflict of Interest Disclosures

Project Information

Laurel K. Leslie, MD, MPH
Tufts Medical Center, Inc.
Comparative Effectiveness of Adolescent Lipid Screening and Treatment Strategies

Key Dates

December 2012
November 2017

Study Registration Information


Has Results
Award Type
Health Conditions Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Populations Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Last updated: March 4, 2022