Final Research Report

View this project's final research report.

Peer-Review Summary

Peer review of PCORI-funded research helps make sure the report presents complete, balanced, and useful information about the research. It also assesses how the project addressed PCORI’s Methodology Standards. During peer review, experts read a draft report of the research and provide comments about the report. These experts may include a scientist focused on the research topic, a specialist in research methods, a patient or caregiver, and a healthcare professional. These reviewers cannot have conflicts of interest with the study.

The peer reviewers point out where the draft report may need revision. For example, they may suggest ways to improve descriptions of the conduct of the study or to clarify the connection between results and conclusions. Sometimes, awardees revise their draft reports twice or more to address all of the reviewers’ comments. 

The awardee made the following revisions in response to peer review:

  • The awardee added information about patient and stakeholder engagement and details about the intervention. The awardee also elaborated on usual-care conditions.
  • The awardee noted the lack of information about the content of usual care as a study limitation. Further, the awardee revised the report’s conclusion to indicate that the intervention condition was superior to a referral to a primary care physician.
  • The awardee provided the rationale for subgroup analyses based on gender, depressive symptoms, and health literacy. The investigator explained that the addition of these analyses came after completion of primary analyses. The awardee therefore described the analyses as exploratory.
  • The awardee explained that recruitment focused on patients who lacked a regular primary care physician because such a lack is typical in the rural Appalachian region where the study took place. Also, the awardee explained that including participants who did have a regular physician would have introduced too much heterogeneity to test for treatment differences.

Conflict of Interest Disclosures

Project Information

Debra K. Moser, PhD, RN, FAAN
University of Kentucky
Reducing Health Disparities in Appalachians with Multiple Cardiovascular Disease Risk Factors

Key Dates

December 2012
May 2018

Study Registration Information


Has Results
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Populations Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
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Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Research Priority Area
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Last updated: March 4, 2022