Final Research Report
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Peer review of PCORI-funded research helps make sure the report presents complete, balanced, and useful information about the research. It also assesses how the project addressed PCORI’s Methodology Standards. During peer review, experts read a draft report of the research and provide comments about the report. These experts may include a scientist focused on the research topic, a specialist in research methods, a patient or caregiver, and a healthcare professional. These reviewers cannot have conflicts of interest with the study.
The peer reviewers point out where the draft report may need revision. For example, they may suggest ways to improve descriptions of the conduct of the study or to clarify the connection between results and conclusions. Sometimes, awardees revise their draft reports twice or more to address all of the reviewers’ comments.
Peer reviewers commented, and the researchers made changes or provided responses. The comments and responses included the following:
- The reviewers noted that the researchers did not find any benefit from the intervention based on the planned analyses. Positive findings were based on exploratory analyses comparing the experimental group to its baseline scores. The researchers acknowledged this and the need to be clear about the negative primary outcome. They revised the text.
- Reviewers said the absence of a theoretical framework made it difficult to interpret the results of the study. The researchers said that given the lack of understanding about how parental stress affects child asthma outcomes, they reasoned that the mechanism may be complex. They focused their efforts on building parental self-efficacy to manage stress. The researchers also added a figure to illustrate their conceptual model.
- The reviewers noted that several planned analyses, based on the study protocol, were not completed. These included a per-protocol analysis and a comparison to a historical control. The researchers acknowledged that they wanted to include these analyses but did not have the resources to do so. They did add an analysis of intervention fidelity to the final report.
Conflict of Interest Disclosures
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