Final Research Report

View this project's final research report.

Peer-Review Summary

Peer review of PCORI-funded research helps make sure the report presents complete, balanced, and useful information about the research. It also assesses how the project addressed PCORI’s Methodology Standards. During peer review, experts read a draft report of the research and provide comments about the report. These experts may include a scientist focused on the research topic, a specialist in research methods, a patient or caregiver, and a healthcare professional. These reviewers cannot have conflicts of interest with the study.

The peer reviewers point out where the draft report may need revision. For example, they may suggest ways to improve descriptions of the conduct of the study or to clarify the connection between results and conclusions. Sometimes, awardees revise their draft reports twice or more to address all of the reviewers’ comments. 

Reviewers’ comments and the investigator’s changes in response included the following: In response to reviewer requests, the awardee added figures to an appendix showing results for simulation 1 as well as for the other two covariate specifications. The awardee also added a list of variables to the appendix.

  • Responding to reviewer feedback, the awardee clarified that simulation 1, unlike simulation 2, is generalizable because it included prevalent and rare outcome scenarios.
  • The awardee expanded the discussion of how results differ across the simulation scenarios and provided guidance for researchers on determining which results are applicable for their own studies.

Conflict of Interest Disclosures

Project Information

Jessica M. Franklin, PhD
Brigham and Women's Hospital
$997,989
10.25302/3.2018.ME.13035796
Methods for Comparative Effectiveness and Safety Analyses in a High-Dimensional Covariate Space with Few Events

Key Dates

September 2013
December 2017
2013
2018

Study Registration Information

Tags

Has Results
Award Type
Health Conditions Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Last updated: March 4, 2022