Final Research Report

View this project's final research report.

Peer-Review Summary

Peer review of PCORI-funded research helps make sure the report presents complete, balanced, and useful information about the research. It also confirms that the research has followed PCORI’s Methodology Standards. During peer review, experts who were not members of the research team read a draft report of the research. These experts may include a scientist focused on the research topic, a specialist in research methods, a patient or caregiver, and a healthcare professional. Reviewers do not have conflicts of interest with the study.

The peer reviewers point out where the draft report may need revision. For example, they may suggest ways to improve how the research team analyzed its results or reported its conclusions. Learn more about PCORI’s peer-review process here.

In response to peer review, the PI made changes including

  • Providing more information about the measures of caregiver burden, particularly those identified as secondary outcomes. The reviewers had asked for the rationale behind having multiple primary and secondary outcome measures of burden and depression.
  • Expanding the information regarding subgroup analyses by making sure that the abstract, results, and discussion adequately addressed these analyses, particularly as they related to caregiver age.
  • Explaining that the researchers chose not to complete analyses that included an interaction term for subgroup (i.e., age by intervention type) because of the lack of significant differences between intervention groups in the main analyses.
  • Revising the description of study outcomes, particularly those related to subgroups, in response to reviewers’ concerns about the inconsistent reporting of intervention differences by subgroups. Detailed subsections for subgroup analyses, one for primary outcomes and one for secondary outcomes, addressed these concerns

Conflict of Interest Disclosures

Project Information

Jose Alejandro Luchsinger, MD, MPH
Columbia University Health Sciences
Northern-Manhattan Hispanic Caregiver Intervention Effectiveness Study (NHiCE)

Key Dates

September 2013
May 2018

Study Registration Information


Has Results
Award Type
Health Conditions Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Populations Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Last updated: March 4, 2022