The Mid-South Clinical Data Research Network (CDRN) was founded in 2014 under PCORI Phase I funding. Our CDRN encompasses three large networks with multiple health systems, ambulatory practices and hospital across the country. In Phase II, our CDRN will include additional health systems in that expand our reach across the South, and increase access to research and informatics expertise. Our expanded CDRN includes a diverse array of academic and community hospitals, primary care and specialty practices, and community health centers in rural and urban areas, reaching over 9 million patients in the South, plus 14 million patients nationally.
Phase I funding has transformed our capability to conduct pragmatic research. We have developed significant infrastructure, including:
- CDRN organizational structure and policies;
- the PCORnet common data model (CDM);
- informatics tools for electronic patient identification, contact, consent, surveying, and payment;
- stakeholder engagement infrastructure, and surveying of over 1,200 patients and clinicians;
- regulatory processes; and
- operational processes for assessing and acting on requests for CDRN resources.
We have also successfully recruited patients, including the surveying of over 6,000 patients for our weight, coronary heart disease, and sickle cell disease cohorts. Our new partner has already begun efforts to merge processes with the Mid-South CDRN, including implementing the CDM and initial searches.
Conducting research will be the main focus of Phase II. Our CDRN has already collaborated on the planning and conduct of over 30 different research projects, including projects with CDRNs, patient-powered research networks, researchers from academic institutions, and the health industry. We are also actively participating in the PCORI-funded pragmatic trial on aspirin dosing and the planned PCORI observational studies on obesity. Phase II will focus on continued participation in a wide array of research activities including pre-research and complex queries, observation research, and interventional studies. Our CDRN will also continue to collaborate closely with the four National Institutes of Health–funded Clinical and Translational Science Awards and Institutes sites in our network to ensure synergistic use of resources. We will also initiate an operational model for sustainability.
View more about this project on PCORnet.org.