This research project is in progress. PCORI will post the research findings on this page within 90 days after the results are final.
What is the research about?
Endometrial cancer, or cancer of the uterus, is one of the most common cancers diagnosed in women in the United States. Fortunately, it is very treatable. Three out of four women with this cancer can be cured by a single surgery called a hysterectomy. More than half of women who have had cancer of the uterus also have loss of bladder control, or leaking urine with coughing, sneezing, or lifting. Bladder control problems can also be cured with surgery. Having surgery on the uterus and bladder at the same time may improve quality of life for women who have cancer of the uterus. It may also decrease healthcare costs and medical risks from having a second surgery. However, few cancer surgeons ask patients about bladder control problems at the time of cancer diagnosis or suggest treating both problems in a single surgery.
The research team wants to study quality of life, health, and sexual function in women who have cancer of the uterus. The team wants to compare outcomes for women who have surgery only to treat the cancer with women who have both surgeries at the same time.
Who can this research help?
The results of this study can help women with cancer of the uterus and their doctors decide whether to treat bladder control problems at the same time as cancer.
What is the research team doing?
The research team is recruiting 556 women who have early-stage cancer of the uterus and bladder control problems. During appointments to talk about treating bladder control problems, doctors tell these women that they may be able to treat their cancer and bladder control problems at the same time.
At the start of the study, women answer questions about their quality of life, sexual function, and bladder control problems. The women in the study answer the same questions again 6 weeks, 6 months, and 1 year after treatment. The team is looking to see if the answers are different for women who have surgery for cancer alone or for both conditions, as well as for women who choose not to meet with a surgeon who treats bladder control problems.
Women who have had cancer of the uterus, doctors who treat it, and cancer case managers are working with the research team to plan the study and track its results.