Results Summary

What was the research about?

Almost 230,000 children in the United States have cerebral palsy, or CP. CP is a health problem that affects motor skills, which include the ability to move and to maintain balance and posture. Physical therapy, or PT, is one way to improve motor skills. PT includes exercises, repeated activities, and other actions to improve motor and mental skills.

In this study, the research team compared two PT schedules for children with CP. The first was one hour of PT once a week for 40 weeks. The second was two periods of 10 weekdays each, where children got two hours of PT each day. The team compared how well these two schedules improved children’s health and well-being. They looked at

  • Motor skills and ability to move
  • Physical development
  • Ability to do activities independently
  • Quality of life, social function, and involvement in community activities

The research team also looked at how parents rated working with physical therapists.

What were the results?

Children in both physical therapy groups had improved motor skills and other health outcomes. The two schedules didn’t make a difference in the amount of improvement. Parents in both groups gave positive ratings to working with therapists.

Who was in the study?

The study included 100 children ages 2–8 with cerebral palsy. The average age was 5 years, and 55 percent were boys.

What did the research team do?

The research team first assigned children by chance to one of two PT schedules. If parents didn’t want their children to be assigned by chance, the team let parents choose one of the PT schedules. The team assigned 46 children by chance, while parents of 54 children chose their PT schedule. Of these parents, 26 chose weekly PT and 28 chose everyday PT. Licensed and trained physical therapists provided the PT. The team looked at health outcomes before children started PT and again nine months later.

Parents of children with cerebral palsy, an adult with cerebral palsy, and cerebral palsy support groups helped plan the study.

What were the limits of the study?

Fewer children took part in the study than expected, making it hard to find differences in health outcomes. Future studies could look at how to better support patients with cerebral palsy to take part in studies comparing PT schedules.

How can people use the results?

Parents of children with CP and their healthcare providers can use these results when considering PT schedules.

Final Research Report

View this project's final research report.

Peer-Review Summary

Peer review of PCORI-funded research helps make sure the report presents complete, balanced, and useful information about the research. It also assesses how the project addressed PCORI’s Methodology Standards. During peer review, experts read a draft report of the research and provide comments about the report. These experts may include a scientist focused on the research topic, a specialist in research methods, a patient or caregiver, and a healthcare professional. These reviewers cannot have conflicts of interest with the study.

The peer reviewers point out where the draft report may need revision. For example, they may suggest ways to improve descriptions of the conduct of the study or to clarify the connection between results and conclusions. Sometimes, awardees revise their draft reports twice or more to address all of the reviewers’ comments. 

Peer reviewers commented and the researchers made changes or provided responses. Those comments and responses included the following:

  • The reviewers cautioned the researchers against concluding that there were no primary outcome differences between the weekly and high-intensity physical therapy treatment arms. The reviewers noted that the study did not achieve its anticipated sample size, so the lack of difference comparative improvement could be the result of insufficient power to find the effect rather than an indication that there really is no difference. The researchers acknowledged this alternate interpretation of their study findings and changed their discussion to note that their conclusions of equivalency between the treatment arms should be tempered given low power and wide variation in the results.
  • The reviewers also cautioned the researchers about their conclusions because the study’s sample size was small and loss to follow-up was high. The researchers disagreed that the sample size was small, stating that the sample size would be considered medium or large in pediatric rehabilitation studies. The researchers did revise their report to emphasize the power analysis and low power of the study, but also noted that there are few studies of long-term outcomes in pediatric physical rehabilitation, so the results are still a major contribution to the field.
  • Reviewers commented that the study took an ableist perspective, based on the medical model of disability, with the goal of changing people to experience more typical development, rather than the social model which suggests society should change to create supports for individuals with disabilities so they can participate more fully in life. The researchers edited the report to acknowledge the social model of disability, reduce language that may be perceived as ableist, and state that this study took place within the medical model of care.

Conflict of Interest Disclosures

Project Information

Jill C. Heathcock, MPT, PhD
The Ohio State University
$2,472,372
10.25302/05.2021.CER.150731899
Comparing Two Schedules of Physical Therapy for Children with Cerebral Palsy

Key Dates

May 2016
January 2021
2016
2021

Study Registration Information

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Health Conditions Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Populations Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Last updated: November 30, 2022