Results Summary

What was the research about?

Depression is a mental health problem that makes people feel sad or hopeless. Many adults who are lesbian, gay, bisexual, transgender, or queer, or LGBTQ+, experience depression.

In this study, the research team compared two ways to improve depression:

  • Staff training alone. The team trained clinic staff and clinicians in depression care. Training taught ways to keep patients safe, screen for symptoms, educate patients, and refer patients to depression services. Clinicians also learned about medicines and therapy to treat depression.
  • Staff training plus resilience classes for people receiving services. People with depression received care from staff who received the same training. They could also attend seven weekly classes led by community health workers. Classes taught ways to improve mood and recover quickly from setbacks. They also got follow-up text messages on class topics and how to get care when needed.

The research team looked at how well these two ways worked for people receiving services from local clinics. These clinics mainly serve people who identify as LGBTQ+.

Who was in the study?

The study included 253 adults with depression. All were receiving services at local clinics in Los Angeles and New Orleans. Of these, 34 percent were Hispanic, 29 percent were Black or African American, 28 percent were White, and 9 percent were another race or ethnicity. The average age was 42. Also, 66 percent were male, 27 percent were female, 4 percent were transgender, and 4 percent didn’t identify as one gender. Eighty-eight percent identified as LGBTQ+ or as men who have sex with men.

What did the research team do?

The research team assigned people by chance to one of two groups: staff training alone or staff training plus resilience classes for people receiving services. At the start of the study, and again 6 and 12 months later, the team surveyed people by phone. They asked about depression symptoms, quality of life, ability to recover quickly from setbacks, and mental well-being.

Adults who identify as LGBTQ+, community agencies, and LGBTQ+ health advocates helped to design and conduct the study.

What were the results?

PCORI is committed to making full information on all funded research projects publicly available. This summary doesn’t include results from or the limits of this study because the research team hasn’t yet responded to peer reviewers’ comments on their work. We will post the results and additional information if the research team completes the peer review process. Click here to learn more about the peer review process.

Genetic Alliance and PRIDEnet formerly were Network Partners in PCORnet®, the National Patient-Centered Clinical Research Network. PCORnet® has been developed with funding from the Patient-Centered Outcomes Research Institute (PCORI®).

Final Research Report

This project's final research report is expected to be available by July 2024.

Peer-Review Summary

The Peer-Review Summary for this project will be posted here soon.

Conflict of Interest Disclosures

Project Information

Bowen Chung, MD, MS
University of California, Los Angeles
Resilience Against Depression Disparities (RADD)

Key Dates

March 2016
March 2022

Study Registration Information


Has Results
Health Conditions Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Populations Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Last updated: November 2, 2023