Final Research Report
View this project's final research report.
Related Journal Citations
Peer review of PCORI-funded research helps make sure the report presents complete, balanced, and useful information about the research. It also assesses how the project addressed PCORI’s Methodology Standards. During peer review, experts read a draft report of the research and provide comments about the report. These experts may include a scientist focused on the research topic, a specialist in research methods, a patient or caregiver, and a healthcare professional. These reviewers cannot have conflicts of interest with the study.
The peer reviewers point out where the draft report may need revision. For example, they may suggest ways to improve descriptions of the conduct of the study or to clarify the connection between results and conclusions. Sometimes, awardees revise their draft reports twice or more to address all of the reviewers’ comments.
Peer reviewers commented and the researchers made changes or provided responses. Those comments and responses included the following:
- The reviewers asked the researchers to provide more information about disease severity among patient participants in the study. One reviewer noted that differences in disease severity among patients could affect the reliability measurements for the patient-reported outcomes measures under investigation. The researchers said that all patients had metastatic cancer and were high risk, but there was no additional information about differences in patient symptoms. The researchers acknowledged that variability in patient symptoms within each clinic site could affect reliability measures and modified their reliability calculations to account for patient-level factors. The researchers also moved their risk adjustment calculations step to occur before the reliability analyses. These changes in methods led to a reduction in the calculated reliability of the patient-reported outcomes measures.
- The reviewers were concerned that the study did not ask clinicians about treatments for fatigue and loss of appetite, two symptoms that stakeholders identified as important. The researchers explained that clinicians do not have effective treatments for fatigue or loss of appetite related to cancer, although these are important and impactful symptoms in cancer care. The researchers felt that they could not evaluate the quality of cancer care based on these symptoms, however, because clinicians cannot control them.
Conflict of Interest Disclosures
Patient / Caregiver Partners
- Mary Lou Smith, JD, MBA, Research Advocacy Network
- Patricia Spears, Cancer Information and Support Network
- Cindy Geoghegan, Patients and Partners
Other Stakeholder Partners
- American Society of Clinical Oncology (ASCO)
- National Committee for Quality Assurance (NCQA)
- Minnesota Community Measurement (MNCM)
Study Registration Information
- Has Results