Final Research Report
View this project's final research report.
Related Journal Citations
Peer review of PCORI-funded research helps make sure the report presents complete, balanced, and useful information about the research. It also assesses how the project addressed PCORI’s Methodology Standards. During peer review, experts read a draft report of the research and provide comments about the report. These experts may include a scientist focused on the research topic, a specialist in research methods, a patient or caregiver, and a healthcare professional. These reviewers cannot have conflicts of interest with the study.
The peer reviewers point out where the draft report may need revision. For example, they may suggest ways to improve descriptions of the conduct of the study or to clarify the connection between results and conclusions. Sometimes, awardees revise their draft reports twice or more to address all of the reviewers’ comments.
Peer reviewers commented and the researchers made changes or provided responses. Those comments and responses included the following:
- The reviewers lauded the researchers’ work to better predict patient diagnoses and other traits to account for missing information in the electronic health record. The reviewers asked that the researchers provide more information about the reasoning behind the Bayesian approaches developed in this study. The researchers responded by adding results of several comparable methods to their report to demonstrate the superiority of the Bayesian methods.
- The reviewers asked how useful this work would be for clinical research. The researchers responded that the results of this study and their use of simulation studies like the work completed in this research have the potential to be very useful for clinical research. However, their approach must first be compared to a gold standard, even though they also note that one does not currently exist.
Conflict of Interest Disclosures
Patient / Caregiver Partners
Douglas Lunsford (parent), Nationwide Children’s Hospital Drew Wittman
Other Stakeholder Partners
Nikki Highfield, Cincinnati Children’s Hospital Rohan Henry, Nationwide Children’s Hospital Robert Siegel, Cincinnati Children’s Hospital Monika Chaudhari, Nationwide Children’s Hospital
Study Registration Information
- Has Results