Final Research Report

View this project's final research report.

Peer-Review Summary

Peer review of PCORI-funded research helps make sure the report presents complete, balanced, and useful information about the research. It also assesses how the project addressed PCORI’s Methodology Standards. During peer review, experts read a draft report of the research and provide comments about the report. These experts may include a scientist focused on the research topic, a specialist in research methods, a patient or caregiver, and a healthcare professional. These reviewers cannot have conflicts of interest with the study.

The peer reviewers point out where the draft report may need revision. For example, they may suggest ways to improve descriptions of the conduct of the study or to clarify the connection between results and conclusions. Sometimes, awardees revise their draft reports twice or more to address all of the reviewers’ comments. 

Peer reviewers commented and the researchers made changes or provided responses. Those comments and responses included the following:

  • The reviewers stated that it was unclear how the causal framework, with various causal effect definitions, was connected to the study’s proposed models and simulation results. The researchers added more information on causal methods in the background section of the report, including sections on causal identification along with an example. The researchers noted that they added material on identification of causal estimates for cluster randomized trials, but that the extension of this work to stepped wedge trial designs would occur in future research.
  • The reviewers noted a few instances where the models and equations used different notations, with no explanation for these differences. The researchers explained that they combined information from eight different papers in this final research report, creating challenges for continuity. The researchers revised the report by attempting to orient the reader to notational changes that could create confusion. 

Conflict of Interest Disclosures

Project Information

Patrick Heagerty, PhD
University of Washington
Learning Within Health Care Delivery Systems: Design, Analysis, and Interpretation of Longitudinal Cluster Randomized Trials

Key Dates

April 2016
June 2021

Study Registration Information


Has Results
Award Type
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Last updated: April 26, 2022