Final Research Report

This project's final research report is expected to be available by September 2022.

Peer-Review Summary

Peer review of PCORI-funded research helps make sure the report presents complete, balanced, and useful information about the research. It also assesses how the project addressed PCORI’s Methodology Standards. During peer review, experts read a draft report of the research and provide comments about the report. These experts may include a scientist focused on the research topic, a specialist in research methods, a patient or caregiver, and a healthcare professional. These reviewers cannot have conflicts of interest with the study.

The peer reviewers point out where the draft report may need revision. For example, they may suggest ways to improve descriptions of the conduct of the study or to clarify the connection between results and conclusions. Sometimes, awardees revise their draft reports twice or more to address all of the reviewers’ comments. 

Peer reviewers commented and the researchers made changes or provided responses. Those comments and responses included the following:

  • The reviewers were impressed with the researchers’ transparency regarding the problems they faced implementing this study and their willingness to discuss the lessons learned.
  • One reviewer questioned the impetus for this research, questioning the need to conduct a large randomized controlled trial comparing physician palliative care home visits to physicians meeting with patients using telehealth with registered nurses conducting home visits. The researchers acknowledged that in the postpandemic environment it may not seem as necessary to test whether patient outcomes are the same with in-person and telehealth care, but when the study was initially devised and conducted this was the major question in the field.
  • The reviewers suggested that many of the problems the researchers faced could have been uncovered using a different study design instead of implementing a full-scale randomized controlled trial. The researchers agreed that in hindsight, a stepped wedge research design could have given them more warning about some of the obstacles they would face in implementing the study. However, the researchers noted that such a design would be less appropriate to evaluate comparative effectiveness and more appropriate to evaluate how the telehealth intervention could be integrated in a palliative care practice. The stepped wedge design would also not have solved some of the challenges they faced with this study, including technological challenges and workforce shortages.

Conflict of Interest Disclosures

Project Information

Huong Q. Nguyen, PhD, RN
Richard Mularski, MD, MSHS
Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
A Non-Inferiority Comparative Effectiveness Trial of Home Based Palliative Care in Older Adults (HomePal)

Key Dates

September 2017
December 2021

Study Registration Information


Has Results
Health Conditions Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Populations Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Last updated: May 18, 2022