Seven million US women and 5 million men experience IPV annually. Although the Affordable Care Act mandates coverage for IPV screening, compliance with this mandate is hampered by lack of evidence about patient-centered screening methods. The West Virginia AWARE (Asking Women About Relationship Experiences) Collaborative works to transform the healthcare system’s response to IPV to ensure the safety and well-being of patients experiencing IPV. By providing a forum for sharing, advocacy, education, planning, and action, this group of diverse stakeholders works to explore our communities’ priorities and achieve their goals in a manner that values the perspectives of those experiencing IPV and their families. Our collective goal is to develop a patient-centered research proposal focused on improving IPV screening in healthcare settings. In Tier II, we intend to build on the momentum and progress generated in Tier I by (1) strengthening and expanding our collaborative, (2) solidifying our communication and governance structure, and (3) transforming our preliminary comparative effectiveness research ideas into a final patient-centered, comparative effectiveness research question. In anticipation of submission of a Tier III research proposal, our final comparative effectiveness research question will be developed and shaped by input from IPV survivors and a diverse group of stakeholders who share the common goal of informing safe, effective IPV screening in healthcare settings.