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  • Research & Results
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  • Comparing Two Ways to Increase HPV Te...

Comparing Two Ways to Increase HPV Testing for Cervical Cancer Screening

Sign Up for Updates to This Study  

Project Summary  

This research project is in progress. PCORI will post the research findings on this page within 90 days after the results are final.

What is the research about?

When new clinical practice guidelines come out, it can be hard for doctors to change their practices. For example, guidelines now recommend that doctors use the test for human papilloma virus, or HPV, as the primary test to screen for cervical cancer, either alone or with the Pap test, for many women. But despite this guidance, doctors don’t always use the HPV test.

In this study, the research team is comparing two ways the Kaiser Permanente Southern California healthcare system, or KPSC, is using to try to increase doctors’ use of primary HPV screening. The first way is called a guided local-tailored approach. In this approach, clinics create a local project team that identifies barriers to doctors’ use of primary HPV screening. Then the team selects and applies strategies from an existing list to address those barriers. The second way is called a hybrid usual care approach. This approach involves standard education from KPSC followed by the clinic’s usual process for adopting new guidelines.

Who can this research help?

Results may help healthcare systems when considering ways to change care to reflect new guidelines or evidence.

What is the research team doing?

The research team is assigning 12 KPSC clinics by chance to either the guided local-tailored or hybrid usual care approach. The team is looking at health records for women ages 30–65 to see how often doctors order cervical cancer screening with primary HPV testing. Also, the team is asking doctors, nurses, and patients about their experiences switching to primary HPV testing.

Patients and providers are helping to choose study outcomes and design ways to collect data.

Research methods at a glance

Design Elements Description
Population 12 KPSC medical centers with 1,400 providers and 10,000 patients
Interventions/
Comparators
  • Guided local-tailored approach
  • Hybrid usual care approach
Outcomes

Primary: provider-level uptake of primary HPV screening

Secondary: patient and provider knowledge of HPV test, patient and provider satisfaction with transition to primary HPV testing for routine cervical cancer screening, patient emotional reaction to HPV test and positive HPV test results, provider delivery of education, provider resistance to the new screening test

Timeframe 2-month follow-up for primary outcome

Project Details

Principal Investigator
Chun Chao, PhD, MS
Project Status
In progress; Not yet recruiting
Project Title
Comparing Strategies for Implementing Primary HPV Testing for Routine Cervical Cancer Screening
Board Approval Date
November 2018
Project End Date
April 2023
Organization
Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
Year Awarded
2018
State
California
Project Type
Research Project
Health Conditions  
Cancer
Cervical Cancer
Infectious Diseases
HPV and other Sexually Transmitted Infections
Intervention Strategies
Other Health Services Interventions
Policy Interventions
Training and Education Interventions
Populations
Racial/Ethnic Minorities
Women
Funding Announcement
Communication and Dissemination Research
Project Budget *  
$2,806,465
Study Registration Information
HSRP20194148
https://clinicaltrials.gov/ct2/show/NCT04371887

*All proposed projects, including requested budgets and project periods, are approved subject to a programmatic and budget review by PCORI staff and the negotiation of a formal award contract.

Page Last Updated: 
September 11, 2020

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PCORI 2021 and Beyond: Opportunities for Funding and Involvement in Patient-Centered Research
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Board of Governors Meeting: February 9, 2021
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