The Research Action for Health Network (REACHnet) CRN is a partnership of four health systems and three academic research institutions in Louisiana and Texas led by the Louisiana Public Health Institute (LPHI). REACHnet is committed to the conduct of patient-centered outcomes research that will in turn have a real effect on health delivery systems and health outcomes. The network is advancing more complete and comprehensive data sets for research by linking clinical data from its participating sites to complementary data sources, including both Medicare and Medicaid claims and claims from private health plans. This data linkage provides a more complete picture of patients’ healthcare experience and is essential for providing the necessary depth of data for real-world evidence studies.
COVID-19-Related Project Enhancement
Recent data suggests the development of coagulopathy as a result of the inflammatory response to SARS-CoV-2 infection is associated with poorer outcomes in patients with COVID-19. The enhancement to this project utilizes the PCORnet Distributed Research Network Operations Center, vanguard Clinical Research Network (CRN) sites, and the PCORnet COVID-19 Common Data Model (CDM) to optimize and validate key COVID-19 data elements related to the treatment and outcomes associated with COVID-19 coagulopathy.
This initial work will help to inform future work to better understand the prevalence and role of coagulopathy in COVID-19 and potential treatment options. In the enhancement:
Enhancement Award Amount: $28,000
To maximize research opportunities, REACHnet actively engages with a multitude of different stakeholders, including patients, clinicians, health system leaders, researchers, and community members. The network is committed to integrating the perspectives of diverse stakeholders into the network’s infrastructure, research strategies, and daily operations. To uphold REACHnet’s patient-centric model, patient engagement is a network priority. To ensure successful engagement of the patient community, REACHnet created the Health in Our Hands Patient Network Registry. The research registry provides opportunities for patient partnership with the research community and study participant recruitment, as well as a platform to disseminate research results.
REACHnet is governed by a council of co-principal investigators (PIs), which consists of the network PI, site-level PIs, and two patient investigators. The council manages the data infrastructure, research governance, and overall operations of the network based on REACHnet’s Research Participation Policy and broader regulatory framework. Routine operations for REACHnet are based out of the Network Coordinating Center at LPHI.
PCORnet is intended to serve as a national resource for conducting rapid, efficient, patient-centered observational and interventional randomized research that improves healthcare delivery and health outcomes. Over the course of this project period, REACHnet will enhance and optimize its infrastructure to support a variety of patient-centered studies by:
- Ensuring meaningful engagement of patients, caregivers, clinicians, delivery systems, payers, and researchers, in all phases of the research process
- Operating through a network model in which data remains at the source while allowing approved researchers within and outside the network to access it securely through a central point
- Facilitating the public sharing of resources and reusable tools to make research more efficient and reproducible
- Using the PCORnet CDM, which standardizes the data collected when patients receive care so that it is comparable across health systems and can be used for patient-centered outcomes research
- Using streamlined processes such as one central IRB for studies involving multiple systems and standardized data use agreements, to enable research to be quicker and more efficient
|Title||Research Action for Health Network (REACHnet)|
|Network Design||Clinical Research Network|
|Lead Partner||Louisiana Public Health Institute|
|Other Partners||Baylor Scott & White Health Research Institute
Ochsner Health System
Tulane Medical Center
University Medical Center New Orleans
Tulane University Schools of Medicine & Public Health
Louisiana State University Health Sciences Center
Pennington Biomedical Research Center
About PCORnet® Clinical Research Networks (CRNs)
|PCORI funded the development of PCORnet®, the National Patient-Centered Clinical Research Network, to make it easier and more efficient to conduct research. PCORnet is made up of Partner Networks that harness the power of large amounts of health data and patient partnerships. Clinical Research Networks (CRNs) are one type of network supported by PCORI. CRNs consist of two or more healthcare systems, including hospitals, integrated delivery systems, and federally qualified health centers. Each CRN transforms data gathered from routine patient care across its participating health systems to a consistent format, the Common Data Model (CDM), to enable rapid response to research-related questions.|
Related Journal Citations
- Awarded; Contract not executed
- PCORnet: Clinical Research Network (CRN) 2020
The state where the project originates, or where the primary institution or organization is located.