Project Summary

View Topic Brief*

Ablation is a treatment strategy that aims to restore normal sinus rhythm and reduce symptoms for patients with atrial fibrillation, a common heart arrythmia. PCORI is commissioning a topic brief on ablation for the treatment of atrial fibrillation. PCORI seeks to understand the breadth and quantity of recent evidence on ablation strategies to support funding decisions for future comparative effectiveness research and evidence synthesis.

The goal of the topic brief is to identify key ablation strategies; provide an overview of clinical practice guidelines, systematic reviews, and randomized controlled trials that assess ablation for atrial fibrillation, and highlight evidence gaps.

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*The content included in this document does not necessarily represent the views of PCORI, its Board of Governors, or Methodology Committee. This work is made available under a Creative Commons Attribution-NonCommerical-NoDerivatives 4.0 International License (CC-BY-NC-ND 4.0 International). For more information:

Project Information

Leila Kahwati, MD, MPH

Key Dates

May 2022


Project Status
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Last updated: November 7, 2022