Project Summary

This research project is in progress. PCORI will post the research findings on this page within 90 days after the results are final.

What is the research about?

Uncontrolled high blood pressure, or BP, causes more than 500,000 deaths each year in the United States. Tracking BP at home can help lower BP and improve patients’ health. With home tracking, patients take their BP using an electronic device that sends their BP values to their care team. The care team can then adjust BP treatment between clinic visits. But questions remain about how much support patients need to successfully track BP at home.

In this study, the research team is comparing two ways to support patients with home BP tracking:

  • Enhanced usual care, or EUC. Patients use a home BP tracker. They also receive information from their doctor on diet, exercise, and how to control their BP.
  • Telemonitoring with team-based care, or TTC. Patients use a home BP tracker and work with a care team. Care teams include clinicians, such as a doctor, nurse practitioner, or physician assistant, and a clinical pharmacist. Care teams provide support over the phone or via telehealth twice per month in the first 2 months and then monthly for 10 months. Care teams teach patients to control BP and help adjust medicines as needed. Care teams also help patients to problem-solve and refer them to support services. Services may include help to access transportation, reduce medicine costs, or improve nutrition and exercise.

Who can this research help?

Results may help clinic administrators and clinicians when considering ways to help patients manage high BP.

What is the research team doing?

The research team is recruiting 780 adults with uncontrolled BP from 14 primary care practices in North Carolina. The team is assigning patients by chance to receive EUC or TTC.

The research team is checking patients’ BP at the start of the study and again 6 and 12 months later. The team is also looking to see if effects of being in the EUC or TTC group vary by patient traits such as age, sex, or race.

Patients with high BP and clinicians are helping to plan and conduct this study.

Research methods at a glance

Design Element Description
Design Randomized controlled trial
Population 780 adults ages 18 and older with a history of high BP from 1 of 14 primary care clinics across North Carolina
  • EUC
  • TTC

Primary: change in systolic blood pressure at 6 months

Secondary: change in systolic blood pressure at 12 months, improved systolic blood pressure control

Timeframe Timeframe Length of follow-up for collecting data on primary outcomes. View Glossary 6-month follow-up for primary outcome

Project Information

Doyle Cummings, PharmD
Jacqueline Halladay, MD, MPH
Brody School of Medicine at East Carolina University
Carolina Consortium to Improve Blood Pressure Control in Vulnerable Populations

Key Dates

July 2022
January 2029


Award Type
Health Conditions Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Populations Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Last updated: October 4, 2023