Neuman MD, Feng R, Carson JL, Gaskins LJ, Dillane D, Sessler DI, Sieber F, Magaziner J, Marcantonio ER, Mehta S, Menio D, Ayad S, Stone T, Papp S, Schwenk ES, Elkassabany N, Marshall M, Jaffe JD, Luke C, Sharma B, Azim S, Hymes RA, Chin KJ, Sheppard R, Perlman B, Sappenfield J, Hauck E, Hoeft MA, Giska M, Ranganath Y, Tedore T, Choi S, Li J, Kwofie MK, Nader A, Sanders RD, Allen BFS, Vlassakov K, Kates S, Fleisher LA, Dattilo J, Tierney A, Stephens-Shields AJ, Ellenberg SS; REGAIN Investigators. Spinal Anesthesia or General Anesthesia for Hip Surgery in Older Adults. N Engl J Med. 2021 Oct 9. doi: 10.1056/NEJMoa2113514. Epub ahead of print. PMID: 34623788.
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Every year, many of the 250,000 people who have surgery for hip fracture in the United States receive general anesthesia, but the use of regional anesthesia injected into the spine is rapidly increasing. A PCORI-funded randomized trial led by researchers at the University of Pennsylvania found that the two approaches are equally safe and effective. Published in the New England Journal of Medicine, the study of 1,600 patients 50 and older at 46 hospitals across the United States and Canada found rates of survival, ability to walk, and post-operative delirium were similar for patients who had either anesthesia. The results could facilitate decision making about which option best fits a patient’s preferences.