On November 15, 2022, PCORI announced the approval of funding totaling $96 million for 18 new research studies and $5 million for two new implementation projects. View all the approved funding awards below.

Research Studies

Broad Pragmatic Studies (Addressing Disparities)
Treatment with Endovascular Intervention for Stroke Patients with Existing Disability Eva Mistry, MD, MS
J Mocco, MD, MS
University of Cincinnati
Broad Pragmatic Studies (Assessment of Prevention, Diagnosis, and Treatment Options)
Comparative Effectiveness of an Individualized Model of Hemodialysis versus Conventional Hemodialysis Mariana Murea, MD
Peter Kotanko, MD
Wake Forest University Health Sciences
Optimizing the Outcomes of Adults with Gram-Negative Bloodstream Infections Pranita Tamma, MD, MHS
Sara Cosgrove, MD, MS
Johns Hopkins University School of Medicine
Broad Pragmatic Studies (Communication and Dissemination Research)
Promoting Shared Decision Making for Decisions about Treatment of Severe Aortic Stenosis Karen Sepucha, PhD
Sammy Elmariah, MD, MPH
Massachusetts General Hospital
Broad Pragmatic Studies (Improving Healthcare Systems)
Effectiveness of Interventions to Improve Resiliency and Burnout in Behavioral Health Residential Staff Stephen Bartels, MD, MS Massachusetts General Hospital
Reducing Caregiver Burden and Improving Outcomes for Children with Tracheostomies Living at Home Karen Sepucha, PhD
Christopher Hartnick, MD, MS
Massachusetts General Hospital
Improving Methods for Conducting Patient-Centered Outcomes Research
Can A/B Testing Be Adapted into an Ethical and Useful Approach to Patient-Centered Outcomes Research? James Flory, MD, MS Memorial Sloan Kettering Cancer Center
Data-Adaptive Readmissions Models for Heterogeneous and Longitudinal Data Jared Huling, PhD Regents of the University of Minnesota
Develop Novel Methods to Identify and Characterize Family Relationships from Electronic Health Data Toan Ong, PhD
Lisa Schilling, MD, MSPH
University of Colorado Denver
Diagnostic Tools for Quality Improvement of Machine Learning-Based Clinical Decision Support Systems Jean Feng, PhD, MS University of California, San Francisco
Fast and Robust Weighting Methods for Targeted Comparative Effectiveness Research Jose Zubizarreta, PhD President and Fellows of Harvard College
Transportability of Machine Learning-Enabled Confounding Control Methods Across EHR Databases Richard Wyss, PhD, MS Brigham and Women's Hospital
Brief Interventions for Adolescent Alcohol Use
Adolescent-Only SBI versus Family-Based SBI in Primary Care for Adolescent Alcohol Use Aaron Hogue, PhD Partnership to End Addiction

Comparing Scalable, Technology-Driven, Brief Intervention Packages for Youth Alcohol Use

Maureen Walton, PhD, MPH
Erin Bonar, PhD, MPH
Regents of the University of Michigan
Testing Scalable, Broad-Reach School-Based Brief Interventions for Alcohol Use Randi Schuster, PhD, MA Massachusetts General Hospital (The General Hospital Corp.)
Comparative Effectiveness of Interventions Targeting Mental Health in Individuals with Intellectual and Developmental Disabilities
A Comparison of Two School-Based Interventions to Manage Anxiety in Autistic Students Judy Reaven, PhD University of Colorado Denver
Comparing Cognitive-Behavioral Therapy versus Mindfulness-Based Therapy for Autistic Adults Brenna Maddox, PhD
Micah Mazurek, PhD
The University of North Carolina at Chapel Hill
Prevention, Early Identification, and Treatment of Delirium in Older Adults
Hospital Elder Life Program (HELP) vs. Family-Augmented HELP (FAM-HELP) for Prevention of Delirium Sharon Inouye, MD, MPH
Phillip Vlisides, MD
Hebrew Rehabilitation Center

Implementation Projects

Open Competition PFA: Implementation of Findings from PCORI's Research Investments
Employing a Stepped-Wedge Design to Implement an Evidence-Based Psychotherapy for PTSD in Six Large, Diverse Health Care Systems Joan Cook, PhD
Vanessa Simiola, PsyD
Yale University
Implementing Obesity Treatment in Primary Care Utilizing Evidence-Based Structures Jodi Holtrop, PhD
Andrea Nederveld, MD, MPH
University of Colorado Anschutz Medical Campus

What's Happening at PCORI?

The Patient-Centered Outcomes Research Institute sends weekly emails about opportunities to apply for funding, newly funded research studies and engagement projects, results of our funded research, webinars, and other new information posted on our site.

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