PCORI’s Dissemination and Implementation Program currently offers three funding opportunities to support projects that actively facilitate the uptake and integration of evidence from PCORI-funded studies, in the context of related evidence, into real-world practice. Funded implementation projects have budgets between $500,000 and $2.5 million in total costs and project periods up to 3 years.

Examples of PCORI-Funded Implementation Projects

Helping Children's Hospitals Use a Program to Improve Communication with Families

Helping clinicians identify and report possible abuse in children through an emergency department child abuse alert system. Learn more ➤

Limited Competition: Implementation of PCORI-funded PCOR Results PFA; Awarded December 2017

Shared Decision Making for Bariatric Surgery in Patients with Severe Obesity

Using decision aids to help patients with severe obesity decide whether to have bariatric surgery and, if so, which option is best for them. Learn more ➤

Implementation of Effective SDM Approaches in Practice Settings PFA; Awarded March 2019

Improving Antibiotic Prescribing in Children with Ear, Sinus, and Throat Infections

Implementing a tested outpatient antibiotic stewardship program in multiple health systems to improve prescribing for children. Learn more ➤

Implementation of Findings from PCORI's Major Research Investments PFA; Awarded November 2019

PCORI Implementation Funding Opportunities

If you have previously submitted a Letter of Intent or application to a prior Implementation funding opportunity, you can check the status here.

Recently Awarded PCORI-Funded Implementation Projects

Cycle 2 2020 Implementation Projects

Implementing Advance Care Planning for Dialysis Patients
Studies have shown that patients on dialysis have high, and often unwanted, intensity of care at end of life (EOL). This implementation project will lay the groundwork for broad uptake of Shared Decision Making - Renal Supportive Care (SDM-RSC), a program led by social workers that facilitates EOL planning discussions between dialysis patients and their care teams to ensure patients’ preferences for EOL care are considered. The project team will work with the three largest dialysis organizations in the US to integrate the program into standard practice at 50 dialysis centers across the country.
Principal Investigator: Dale Lupu

Implementing Shared Decision Making for Breast Cancer Using a Coproduction Learning Collaborative
Mastectomy and breast-conserving surgery with radiation are equally effective treatment options for early-stage breast cancer but have distinct tradeoffs. This implementation project will use a learning collaborative approach to support the integration of early-stage breast cancer surgery Option Grid conversation aids, shown in a PCORI-funded study to improve shared decision making, into the clinical workflow at 33 sites with diverse patient populations and broad geographic reach.
Dual Principal Investigators: Glyn Elwyn & Julie Margenthaler

Implementation of a Self-Care Plan for Patients with Acute Heart Failure Discharged from the ED
About 200,000 Americans who visit the Emergency Department (ED) annually for Acute Heart Failure (AHF) are discharged directly to their homes. This implementation project will work with four high-volume EDs in two states to incorporate GUIDED-HF, a self-care coaching program tested in a PCORI-funded study that incorporates components of the American Heart Association’s Get with the Guidelines-Heart Failure program, into standard practice for discharging patients with AHF home from the ED. The project team will train self-care coaches and ED staff to prepare tailored discharge plans with patients, help patients schedule follow-up visits with a provider, and conduct virtual/home visits and follow-up phone calls.
Dual Principal Investigators: Sean Collins and Deonni Stolldorf

Implementation of Health-E You/Salud iTu to Promote Adolescent-Centered Contraceptive Care
A majority of adolescent pregnancies are unplanned due to inconsistent or non-use of effective contraceptive methods. This implementation project will integrate Health-E You/Salud iTu, a PCORI-tested interactive mobile app found to improve uptake of effective contraceptive methods, into standard practice at 27 school-based health centers (SBHCs) with different workflows and serving adolescents from diverse backgrounds, reaching more than 16,000 adolescent girls in 10 states and Washington, DC.
Principal Investigator: Kathleen Tebb

Cycle 2 2020 Dissemination Project

Current Evidence on Liver Transplant versus Medical Management in Urea Cycle Disorders: Opening a Dialogue with Patients, Caregivers, and Providers
Urea cycle disorders (UCDs) are ultra-rare health disorders in which the body cannot get rid of ammonia, potentially leading to brain damage, disability, or death. Dissemination of findings from a PCORI-funded study that compared medical management to liver transplantation for children with UCDs will help families and their clinicians weigh the risks and benefits of these treatment options. This dissemination project will develop educational videos and partner with key stakeholder organizations to promote and distribute the videos to families, UCD providers, and general pediatricians.
Principal Investigator: Nicholas Ah Mew

Cycle 1 2020 Implementation Project

Implementation of Effective Home Oxygen Weaning Strategies in Premature Infants
Many premature infants require home oxygen therapy after they’re discharged home from the hospital. This implementation project will work with 12 medical systems across the country to put in place a Recorded Home Oximetry (RHO) program, tested in a PCORI-funded comparative effectiveness study, that improves management of home oxygen therapy. The program allows parents and their doctors to safely reduce the number of days newborns need to stay on oxygen therapy at home. This project will demonstrate two approaches for hospitals to adopt the RHO program, train 800 providers, and reach 600 families of premature infants per year.
Principal Investigator: Lawrence Rhein

Cycle 3 2019 Implementation Project

Implementing Best-Practice, Patient-Centered Venous Thromboembolism (VTE) Prevention in Trauma Centers
This project builds on a successful PCORI-funded comparative effectiveness research study and follow-up implementation project by scaling up delivery of a point-of-care patient education program found to improve patients’ use of blood clot prevention medication in two types of hospitals. This award will incorporate the program into standard practice at 10 trauma centers across the country to protect vulnerable trauma patients at high risk for dangerous blood clots.
Principal Investigator: Elliott Haut

All PCORI-Funded Implementation Projects

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