The objective of this study was to develop new methods for designing and analyzing small n sequential multiple assignment randomized trials (snSMARTs) that increase efficiency and have low bias.

Project page: Improving Trial Design and Analysis for Treatments for Rare Diseases
Principal Investigator: Kelley M. Kidwell, PhD
Organization: University of Michigan School of Public Health
Original project title: Design and Methodological Improvements for Patient-Centered Small n Sequential Multiple Assignment Randomized Trials (snSMARTs) in the Setting of Rare Diseases
HSRProj ID: 20163133

To cite this document, please use: Kidwell KM, Tamura RN, Braun TM, Wei B, Chao Y-C, Hartman H. (2020). Improving Trial Design and Analysis for Treatments for Rare Diseases. Patient-Centered Outcomes Research Institute (PCORI).


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