Pragmatic clinical studies aim to provide research results that better reflect everyday health care and a wider range of patients. They also seek to produce results that can apply to a greater variety of patients and care situations. In addition, they are designed to take place during routine care in real-life practice settings, such as a typical hospital or clinic. They tend to include a broader range of patients with different circumstances and needs.

Please note that in January 2022, PCORI merged the Pragmatic Clinical Studies and Broad funding opportunities into the renamed Broad Pragmatic Studies, which will simplify the PCORI submission process for applicants, reduce confusion about which funding opportunity is most appropriate for a given study, and assist applicants in their long-range research planning. Learn more here

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