Migraine is a common condition that is disabling for many Americans. Although pharmacologic therapies for migraine prevention exist, nonpharmacologic therapies are an important alternative. In this Topic Brief, the authors identified 164 randomized controlled trials, 27 of which were not summarized by relevant systematic reviews. They concluded that a substantive evidence base for nonpharmacologic migraine prevention therapies exists and that nonpharmacologic interventions remain an important alternative to pharmacotherapy for patients.
Topic briefs like this one identify and categorize the existing effectiveness and comparative effectiveness literature on a medical issue. Using this information, PCORI evaluates the state of the research literature to determine if the current research supports development of a PCORI research product such as a systematic review or a primary research study. The reviews summarize the quality and quantity of research studies. View other topic briefs
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