Addressing Disparities


About 46 million Americans who live in rural areas are more likely than their urban counterparts to die from heart disease, cancer, and stroke. (Source: CDC)


About 36% of the U.S. population belongs to a racial or ethnic minority group, but some minorities experience a disproportionate healthcare burden. (Source: CDC)


PCORI has funded 122 clinical effectiveness research studies and related projects that seek to help patients at risk for disparities and those who care for them make better-informed decisions about their options to improve their health. (As of February 2022)

2023 PCORI Annual Meeting Breakout Session Spotlight

Accountability Matters: How Health Systems Can Meaningfully Address Racism and Discrimination in Care Delivery

Read more about this session.

How PCORI is Advancing Social Determinants of Health Data Collection and Use in Research to Promote Health Equity

Read more about this session.

Study Results that Support Better-Informed Decisions

The PREPARE Study: Reducing the Impact of Asthma on Underserved Populations

An easy-to-use, patient-centered approach to managing moderate to severe asthma improved outcomes for African-American/Black and Hispanic/Latinx adults, according to findings of the PCORI-funded PREPARE study, published in The New England Journal of Medicine. The study was led by Elliot Israel, MD, at Brigham and Women's Hospital in Massachusetts.

Study participants were randomized to receive either usual care or one-time instruction to use inhaled corticosteroids (ICS) when they used an asthma reliever or nebulizer. Those in the ICS group experienced a 15 percent decreased risk of severe asthma exacerbations as well as reduced asthma symptoms and days of impairment compared to those who got usual care.

Evidence Map and Visualization

Social Needs Interventions to Improve Health Outcomes

Social needs refer to adverse social conditions that are associated with poor health and are identified or prioritized based on patients' perspectives. Addressing these social needs could help improve health outcomes and reduce disparities.

This new interactive visualization and an accompanying report summarize the findings from a systematic scoping review of studies on social needs interventions that reported behavioral outcomes, health outcomes, or health care utilization outcomes.

Read a recent blog post about the evidence visualization.

Addressing Disparities Study Spotlights

Addressing Disparities Study Spotlight

Research Addressing Health Disparities in Heart Disease

This PCORI-funded project compared usual care to involving community health workers in an effort to reduce cardiovascular disease risks factors in people living in rural Appalachian Kentucky, which has among the worst cardiovascular health profiles in the country.